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KMID : 0861119980020010175
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Korean Journal of Oriental Preventive Medicine
1998 Volume.2 No. 1 p.175 ~ p.192
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Antitoxic Effects of Semen Mungo Water Extracts against Cadmium Toxicity in Organs of Rats
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Lee Jong-Sub
Lee Ki-Nam
Kim Jeong-Pil
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Abstract
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A study on the antitoxic effects of Semen Mungo extracts against Cadmium Chloride Toxicity in Rats This study was performed to find out the effect of Semen mungo against Cadmium toxicity. The experimental rats were divided into 5 groups such as control group, Cadmium alone treatment group, three simultaneous treatment groups of semen mungo and cadmium. Rats were given pellets administration with three dosage of semen mungo glabrae such as 4mg/kg body weight for four weeks. The results were summarized as follows on: ’ 1. The simultaneously administration of semen mungo and cadmium significantly more decreased cadmium concentration in liver and kidney tissues compared to the administration of cadmium alone.(p<0.05) 2. The simultaneously administration of semen mungo and cadmium significantly more decreased metallothionein concentration in liver and kidney tissues compared to administration of cadmium alone(p<0.05) 3. When liver and kidney tissues were observed with optical microscope obvious changes were visible in those tissues.1
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KEYWORD
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